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1

Hepatitis C viral kinetics with the nucleoside polymerase inhibitor mericitabine (RG7128)

Jeremie Guedj, Harel Dahari, Emi Shudo, Patrick Smith, Alan S. Perelson

Journal:

Year:

2012

Language:

english

File:

PDF, 917 KB

english, 2012

2

Favipiravir for children with Ebola

Bouazza, Naïm, Treluyer, Jean-Marc, Foissac, Frantz, Mentré, France, Taburet, Anne-Marie, Guedj, Jérémie, Anglaret, Xavier, de Lamballerie, Xavier, Keïta, Sakoba, Malvy, Denis, Frange, Pierre

Journal:

Year:

2015

Language:

english

File:

PDF, 109 KB

english, 2015

3

Dose regimen of favipiravir for Ebola virus disease

Mentré, France, Taburet, Anne-Marie, Guedj, Jeremie, Anglaret, Xavier, Keïta, Sakoba, de Lamballerie, Xavier, Malvy, Denis

Journal:

The Lancet Infectious Diseases

Year:

2015

Language:

english

File:

PDF, 304 KB

english, 2015

4

A pharmacokinetic/viral kinetic model to evaluate the treatment effectiveness of danoprevir against chronic HCV

Canini, Laetitia, Chatterjee, Anushree, Guedj, Jeremie, Lemenuel-Diot, Annabelle, Brennan, Barbara, Smith, Patrick F, Perelson, Alan S

Journal:

Antiviral Therapy

Year:

2014

Language:

english

File:

PDF, 395 KB

english, 2014

5

Déraisons de la comparaison ?

Guedj, Jérémy

Journal:

Year:

2014

Language:

french

File:

PDF, 558 KB

french, 2014

6

Second-phase hepatitis C virus RNA decline during telaprevir-based therapy increases with drug effectiveness: Implications for treatment duration

Jeremie Guedj, Alan S. Perelson

Journal:

Year:

2011

Language:

english

File:

PDF, 442 KB

english, 2011

7

Silibinin mode(s) of action against hepatitis C virus: A controversy yet to be resolved

Harel Dahari, Jeremie Guedj, Alan S. Perelson

Journal:

Year:

2011

Language:

english

File:

PDF, 320 KB

english, 2011

8

Design evaluation and optimization for models of hepatitis C viral dynamics

Jeremie Guedj, Caroline Bazzoli, Avidan U. Neumann, France Mentré

Journal:

Statistics in Medicine

Year:

2011

Language:

english

File:

PDF, 287 KB

english, 2011

9

Hepatitis C Viral Kinetics in the Era of Direct Acting Antiviral Agents and Interleukin-28B

Harel Dahari, Jeremie Guedj, Alan S. Perelson, Thomas J. Layden

Journal:

Current Hepatitis Reports

Year:

2011

Language:

english

File:

PDF, 356 KB

english, 2011

10

Joint Modeling of the Clinical Progression and of the Biomarkers' Dynamics Using a Mechanistic Model

Jeremie Guedj, Rodolphe Thiébaut, Daniel Commenges

Journal:

Year:

2011

Language:

english

File:

PDF, 233 KB

english, 2011

11

Estimation of dynamical model parameters taking into account undetectable marker values

Rodolphe Thiébaut, Jérémie Guedj, Hélène Jacqmin-Gadda, Geneviève Chêne, Pascale Trimoulet, Didier Neau, Daniel Commenges

Journal:

BMC Medical Research Methodology

Year:

2006

Language:

english

File:

PDF, 316 KB

english, 2006

12

Understanding silibinin’s modes of action against HCV using viral kinetic modeling

Jeremie Guedj, Harel Dahari, Ralf T. Pohl, Peter Ferenci, Alan S. Perelson

Journal:

Journal of Hepatology

Year:

2012

Language:

english

File:

PDF, 640 KB

english, 2012

13

Innate Immune Tolerance and the Role of Kupffer Cells in Differential Responses to Interferon Therapy Among Patients With HCV Genotype 1 Infection

Lau, Daryl T.–Y., Negash, Amina, Chen, Jie, Crochet, Nanette, Sinha, Mala, Zhang, Yuhong, Guedj, Jeremie, Holder, Sharon, Saito, Takeshi, Lemon, Stanley M., Luxon, Bruce A., Perelson, Alan S., Gale, M

Journal:

Gastroenterology

Year:

2013

Language:

english

File:

PDF, 1.65 MB

english, 2013

14

Clinical trial simulation to evaluate power to compare the antiviral effectiveness of two hepatitis C protease inhibitors using nonlinear mixed effect models: a viral kinetic approach

Cédric Laouénan, Jeremie Guedj, France Mentré

Journal:

BMC Medical Research Methodology

Year:

2013

Language:

english

File:

PDF, 504 KB

english, 2013

15

NIMROD: A program for inference via a normal approximation of the posterior in models with random effects based on ordinary differential equations

Prague, Mélanie, Commenges, Daniel, Guedj, Jérémie, Drylewicz, Julia, Thiébaut, Rodolphe

Journal:

Computer Methods and Programs in Biomedicine

Year:

2013

Language:

english

File:

PDF, 1.34 MB

english, 2013

16

Erratum to “NIMROD: A program for inference via normal approximation of the posterior in models with random effects based on ordinary differential equations” [Comput. Methods Programs Biomed. 111 (2) (2013) 447-458]

Prague, Mélanie, Commenges, Daniel, Guedj, Jérémie, Drylewicz, Julia, Thiébaut, Rodolphe

Journal:

Computer Methods and Programs in Biomedicine

Year:

2014

Language:

english

File:

PDF, 211 KB

english, 2014

17

Modeling viral kinetics and treatment outcome during alisporivir interferon-free treatment in hepatitis C virus genotype 2 and 3 patients

Guedj, Jeremie, Yu, Jing, Levi, Micha, Li, Bin, Kern, Steven, Naoumov, Nikolai V., Perelson, Alan S.

Journal:

Year:

2014

Language:

english

File:

PDF, 447 KB

english, 2014

18

Umbilical artery Doppler assessment: a clear disparity in ultrasound practice in a national survey

Cohen, Jonathan, Guedj, Jeremie, Fries, Nicolas

Journal:

Acta Obstetricia et Gynecologica Scandinavica

Year:

2013

Language:

english

File:

PDF, 158 KB

english, 2013

19

Can we use viral kinetic models to individualize treatment?

Guedj, Jeremie, Nguyen, Thi Huyen Tram

Journal:

Liver International

Year:

2015

Language:

english

File:

PDF, 65 KB

english, 2015

20

Understanding early serum hepatitis D virus and hepatitis B surface antigen kinetics during pegylated interferon-alpha therapy via mathematical modeling

Guedj, Jeremie, Rotman, Yaron, Cotler, Scott J., Koh, Christopher, Schmid, Peter, Albrecht, Jeff, Haynes-Williams, Vanessa, Liang, T. Jake, Hoofnagle, Jay H., Heller, Theo, Dahari, Harel

Journal:

Year:

2014

Language:

english

File:

PDF, 474 KB

english, 2014

21

Pathological prognostic factors in locally advanced rectal carcinoma after neoadjuvant radiochemotherapy: analysis of 113 cases

Sannier, Aurélie, Lefèvre, Jérémie H, Panis, Yves, Cazals-Hatem, Dominique, Bedossa, Pierre, Guedj, Nathalie

Journal:

Year:

2014

Language:

english

File:

PDF, 664 KB

english, 2014

22

Impact of Treatment against Hepatitis C Virus on Overall Survival of Naive Patients with Advanced Liver Disease

Kutala, Blaise K., Guedj, Jeremie, Asselah, Tarik, Boyer, Nathalie, Mouri, Feryel, Martinot-Peignoux, Michelle, Valla, Dominique, Marcellin, Patrick, Duval, Xavier

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 545 KB

english, 2015

23

Patients with chronic hepatitis C without advanced fibrosis and hepatocellular carcinoma: A retrospective clinical–pathological study

K-Kutala, Blaise, Bedossa, Pierre, Guedj, Jeremie, Asselah, Tarik, Martinot-Peignoux, Michelle, Duval, Xavier, Marcellin, Patrick

Journal:

Digestive and Liver Disease

Year:

2015

Language:

english

File:

PDF, 495 KB

english, 2015

24

Nonlinear Mixed-Effect Models for Prostate-Specific Antigen Kinetics and Link with Survival in the Context of Metastatic Prostate Cancer: a Comparison by Simulation of Two-Stage and Joint Approaches

Desmée, Solène, Mentré, France, Veyrat-Follet, Christine, Guedj, Jérémie

Journal:

The AAPS Journal

Year:

2015

Language:

english

File:

PDF, 3.02 MB

english, 2015

25

The hepatitis C virus NS5A inhibitor daclatasvir has a dual mode of action and leads to a new virus half-life estimate

Guedj, Jeremie, Dahari, Harel, Uprichard, Susan L, Perelson, Alan S

Journal:

Expert Review of Gastroenterology and Hepatology

Year:

2013

Language:

english

File:

PDF, 780 KB

english, 2013

26

Mathematical Modeling of Bacterial Kinetics to Predict the Impact of Antibiotic Colonic Exposure and Treatment Duration on the Amount of Resistant Enterobacteria Excreted

Nguyen, Thu Thuy, Guedj, Jeremie, Chachaty, Elisabeth, de Gunzburg, Jean, Andremont, Antoine, Mentré, France, Tanaka, Mark M.

Journal:

PLoS Computational Biology

Year:

2014

Language:

english

File:

PDF, 1.31 MB

english, 2014

27

Quantifying the Diversification of Hepatitis C Virus (HCV) during Primary Infection: Estimates of the In Vivo Mutation Rate

Ribeiro, Ruy M., Li, Hui, Wang, Shuyi, Stoddard, Mark B., Learn, Gerald H., Korber, Bette T., Bhattacharya, Tanmoy, Guedj, Jeremie, Parrish, Erica H., Hahn, Beatrice H., Shaw, George M., Perelson, Ala

Journal:

Year:

2012

Language:

english

File:

PDF, 1.06 MB

english, 2012

28

Modelling hepatitis C therapy—predicting effects of treatment

Perelson, Alan S., Guedj, Jeremie

Journal:

Nature Reviews Gastroenterology and Hepatology (formerly Nature Clinical Practice Gastroenterology and Hepatology)

Year:

2015

Language:

english

File:

PDF, 395 KB

english, 2015

29

Designing a paediatric study for an antimalarial drug including prior information from adults

Petit, Caroline, Jullien, Vincent, Samson, Adeline, Guedj, Jérémie, Kiechel, Jean-René, Zohar, Sarah, Comets, Emmanuelle

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 890 KB

english, 2015

30

Ebola Virus Infection: Review of the Pharmacokinetic and Pharmacodynamic Properties of Drugs Considered for Testing in Human Efficacy Trials

Madelain, Vincent, Nguyen, Thi Huyen Tram, Olivo, Anaelle, de Lamballerie, Xavier, Guedj, Jérémie, Taburet, Anne-Marie, Mentré, France

Journal:

Clinical Pharmacokinetics

Year:

2016

Language:

english

File:

PDF, 1.36 MB

english, 2016

31

Estimating biologically relevant parameters under uncertainty for experimental within-host murine West Nile virus infection

Banerjee, Soumya, Guedj, Jeremie, Ribeiro, Ruy M., Moses, Melanie, Perelson, Alan S.

Journal:

Journal of The Royal Society Interface

Year:

2016

Language:

english

File:

PDF, 1.61 MB

english, 2016

32

Reply

Guedj, Jeremie, Canini, Laetitia, Cotler, Scott, Dahari, Harel

Journal:

Year:

2015

Language:

english

File:

PDF, 464 KB

english, 2015

33

Using the SAEM algorithm for mechanistic joint models characterizing the relationship between nonlinear PSA kinetics and survival in prostate cancer patients

Desmée, Solène, Mentré, France, Veyrat-Follet, Christine, Sébastien, Bernard, Guedj, Jérémie

Journal:

Year:

2016

Language:

english

File:

PDF, 2.26 MB

english, 2016

34

Early HIV RNA decay during raltegravir-containing regimens exhibits two distinct subphases (1a and 1b)

Andrade, Adriana, Guedj, Jeremie, Rosenkranz, Susan L., Lu, Darlene, Mellors, John, Kuritzkes, Daniel R., Perelson, Alan S., Ribeiro, Ruy M.

Journal:

Year:

2015

Language:

english

File:

PDF, 432 KB

english, 2015

35

Case report of Lewy body disease mimicking Creutzfeldt-Jakob disease in a 44-year-old man

Saint-Aubert, Laure, Pariente, Jérémie, Dumas, Herve, Payoux, Pierre, Brandel, Jean-Philippe, Puel, Michèle, Vital, Anne, Guedj, Eric, Lesage, Suzanne, Peoc’h, Katell, Brefel Courbon, Christine, Ory M

Journal:

Year:

2016

Language:

english

File:

PDF, 1.04 MB

english, 2016

36

Favipiravir pharmacokinetics in non-human primates: insights for future efficacy studies of haemorrhagic fever viruses

Madelain, Vincent, Guedj, Jérémie, Mentré, France, Nguyen, Thi Huyen Tram, Jacquot, Frédéric, Oestereich, Lisa, Kadota, Takumi, Yamada, Koichi, Taburet, Anne-Marie, de Lamballerie, Xavier, Raoul, Herv

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 1.76 MB

english, 2016

37

Analysis of the hepatitis C viral kinetics during administration of two nucleotide analogues: sofosbuvir (GS-7977) and GS-0938

Guedj, Jeremie, Pang, Phillip S, Denning, Jill, Rodriguez-Torres, Maribel, Lawitz, Eric, Symonds, William, Perelson, Alan S

Journal:

Antiviral Therapy

Year:

2014

Language:

english

File:

PDF, 624 KB

english, 2014

38

Treatment of hepatitis C with an interferon-based lead-in phase: a perspective from mathematical modelling

Rong, Libin, Guedj, Jeremie, Dahari, Harel, Perelson, Alan S

Journal:

Antiviral Therapy

Year:

2014

Language:

english

File:

PDF, 883 KB

english, 2014

39

Modelling the interaction between danoprevir and mericitabine in the treatment of chronic HCV infection

Canini, Laetitia, Guedj, Jeremie, Chatterjee, Anushree, Lemenuel-Diot, Annabelle, Smith, Patrick F, Perelson, Alan S

Journal:

Antiviral Therapy

Year:

2015

Language:

english

File:

PDF, 786 KB

english, 2015

40

Mathematical modelling of HCV infection: what can it teach us in the era of direct-acting antiviral agents?

Chatterjee, Anushree, Guedj, Jeremie, Perelson, Alan S

Journal:

Antiviral Therapy

Year:

2012

Language:

english

File:

PDF, 687 KB

english, 2012

41

Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies

Best, Katharine, Guedj, Jeremie, Madelain, Vincent, de Lamballerie, Xavier, Lim, So-Yon, Osuna, Christa E., Whitney, James B., Perelson, Alan S.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 841 KB

english, 2017

42

Determining Ribavirin’s mechanism of action against Lassa virus infection

Carrillo-Bustamante, Paola, Nguyen, Thi Huyen Tram, Oestereich, Lisa, Günther, Stephan, Guedj, Jeremie, Graw, Frederik

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 2.32 MB

english, 2017

43

The paradox of highly effective sofosbuvir-based combination therapy despite slow viral decline: can we still rely on viral kinetics?

Nguyen, Thi Huyen Tram, Guedj, Jérémie, Uprichard, Susan L., Kohli, Anita, Kottilil, Shyam, Perelson, Alan S.

Journal:

Scientific Reports

Year:

2017

Language:

english

File:

PDF, 1.76 MB

english, 2017

44

Total Mesenteric Peritonectomy for Peritoneal Metastases (with video)

Cazauran, Jean-Baptiste, Lasseur, Antoinette, Pasquer, Arnaud, Rousset, Pascal, Guedj, Jeremy, Passot, Guillaume, Glehen, Olivier

Journal:

Annals of Surgical Oncology

Year:

2017

Language:

english

File:

PDF, 333 KB

english, 2017

45

Authors' response: Danoprevir pharmacokinetic/viral kinetic model for treating chronic HCV – some considerations

Canini, Laetitia, Guedj, Jeremie, Perelson, Alan S

Journal:

Antiviral Therapy

Year:

2016

Language:

english

File:

PDF, 121 KB

english, 2016

46

Flagellate erythema in systemic sclerosis: A case report

Jannic, Arnaud, Maillet, Jérémy, Rossi, Benjamin, Guedj, Nathalie, Descamps, Vincent, Fantin, Bruno, Le Bozec, Patrick

Journal:

JAAD Case Reports

Year:

2018

Language:

english

File:

PDF, 530 KB

english, 2018

47

Erratum for Madelain et al., “Favipiravir Pharmacokinetics in Nonhuman Primates and Insights for Future Efficacy Studies of Hemorrhagic Fever Viruses”

Madelain, Vincent, Guedj, Jérémie, Mentré, France, Nguyen, Thi Huyen Tram, Jacquot, Frédéric, Oestereich, Lisa, Kadota, Takumi, Yamada, Koichi, Taburet, Anne-Marie, de Lamballerie, Xavier, Raoul, Herv

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2017

Language:

english

File:

PDF, 109 KB

english, 2017

48

Nonlinear joint models for individual dynamic prediction of risk of death using Hamiltonian Monte Carlo: application to metastatic prostate cancer

Desmée, Solène, Mentré, France, Veyrat-Follet, Christine, Sébastien, Bernard, Guedj, Jérémie

Journal:

BMC Medical Research Methodology

Year:

2017

Language:

english

File:

PDF, 2.21 MB

english, 2017

49

Estimating the Time to Diagnosis and the Chance of Spontaneous Clearance during Acute Hepatitis C in HIV-Infected Individuals

Ragonnet, Romain, Deuffic-Burban, Sylvie, Boesecke, Christoph, Guiguet, Marguerite, Lacombe, Karine, Guedj, Jeremie, Rockstroh, Jürgen K., Yazdanpanah, Yazdan

Journal:

Open Forum Infectious Diseases

Year:

2016

Language:

english

File:

PDF, 249 KB

english, 2016

50

Favipiravir pharmacokinetics in Ebola-Infected patients of the JIKI trial reveals concentrations lower than targeted

Nguyen, Thi Huyen Tram, Guedj, Jérémie, Anglaret, Xavier, Laouénan, Cédric, Madelain, Vincent, Taburet, Anne-Marie, Baize, Sylvain, Sissoko, Daouda, Pastorino, Boris, Rodallec, Anne, Piorkowski, Géral

Journal:

PLoS Neglected Tropical Diseases

Year:

2017

Language:

english

File:

PDF, 1.37 MB

english, 2017